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Information :
Chemical
Name : METHOTREXATE - INJECTION (meth-oh-TREX-ate)
Common
uses :
Methotrexate is used to treat certain types of cancer or to control
severe psoriasis or arthritis.
Possible
side effects :
Methotrexate may cause nausea or drowsiness. If these effects persist
or worsen, contact your doctor. Report to your doctor promptly:
mouth sores, diarrhea, fever, persistent sore throat, unusual bleeding
or bruising, black stools, rash, enlarged glands/lymph nodes, bone
pain; unusual pain and skin discoloration; stomach pain or dark
urine. Unlikely but report promptly:
yellowing of the eyes/skin, chest pain, flu-like symptoms, dry cough,
neck stiffness, vision changes, headache, muscle weakness, mental
changes, seizures. Temporary hair loss may occur; normal hair growth
should return after treatment has ended. In the unlikely event you
have an allergic reaction to this drug, seek medical attention immediately.
Symptoms of an allergic reaction include rash, itching, swelling,
fever or trouble breathing. If you notice other effects not listed
above, contact your doctor or pharmacist.
Drug
interactions :
Tell your doctor of all over-the-counter and prescription medication
you may take especially:
etretinate, folic acid, phenytoin, aspirin, NSAIDs (e.g., ibuprofen,
naproxen); sulfa medications and other antibiotics; procarbazine,
digoxin, theophylline, probenecid; other drugs that may harm the
liver (e.g., azathioprine and sulfasalazine). The use of trimethoprim
may interfere with methotrexate blood tests. Tell your doctor if
you use trimethoprim. Do not start or stop any medicine without
doctor or pharmacist approval.
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